| 2021-12-01 | Colts Daily Notebook: DeForest Buckner Plans On Playing Week 13 vs. Houston Texans |
| 2021-12-02 | Hard Knocks In Season Episode 3 Recap: Kenny Moore II's Impact On The Community Shines As Colts Face Off With Tom Brady |
| 2021-12-02 | Colts RB Jonathan Taylor Named AFC Offensive Player Of The Month For November |
| 2021-12-02 | My Cause, My Cleats: What Causes, Organizations Colts Players, Staff Are Supporting In 2021 |
| 2021-12-02 | Colts Daily Notebook: Inside Isaiah Rodgers' Playmaking On Defense, Special Teams |
| 2021-12-03 | Colts Mailbag: Run vs. Pass, AFC South And Wild Card Playoff Race, Hard Knocks |
| 2021-12-03 | Colts Do Not Rule Out Any Players For Week 13 vs. Houston Texans |
| 2021-12-03 | Colts Head Coach Frank Reich Dedicates 60th Birthday Celebration To Fight Against Child Sex Abuse, Trafficking With Support Of kNot Today |
| 2021-12-03 | 5 Things To Watch: Colts vs. Texans, Week 13 |
| 2021-12-04 | Colts Activate S-Khari Willis From Injured Reserve List, Waive S-Josh Jones, Place C-Ryan Kelly on the Reserve/COVID-19 List |
| 2021-12-05 | 2021 Colts Fantasy Preview: Colts vs. Texans, Week 13 |
| 2021-12-05 | Colts Announce Four Inactive Players For Week 13 vs. Houston Texans |
| 2021-12-05 | LIVE BLOG, Colts vs Patriots Week 15 |
| 2021-12-05 | Colts’ Defense Sets Tone, Posts First Road Shutout In Almost Three Decades |
| 2021-12-05 | By The Numbers: Colts 31, Texans 0 (2021 Week 13) |
| 2021-12-06 | Colts Enter Bye Week Knowing Where They Stand In AFC Playoff Race: ‘It’s Go Time’ |
| 2021-12-06 | Colts' Jonathan Taylor Nominated For Week 13 FedEx Air & Ground Player Of The Week |
| 2021-12-06 | 5 Things Learned: Colts vs. Texans, Week 13 |
| 2021-12-06 | Colts Sign QB James Morgan To Practice Squad, Release WR Isaiah McKoy From Practice Squad |
| 2021-12-06 | Colts Daily Notebook: How Players, Coaches Will Spend NFL's Latest Bye Week In 20 Years |
| 2021-12-07 | Colts Nominate CB Kenny Moore II For 2021 Walter Payton Man Of The Year Award |
| 2021-12-08 | Colts Daily Notebook: Inside Jonathan Taylor's Record-Setting Pace In 2021 |
| 2021-12-08 | Colts Mailbag: AFC Playoff Race And Tiebreakers, Bill Belichick, Patriots, Kenny Moore II |
| 2021-12-08 | Colts RB Jonathan Taylor Named FedEx Ground Player of the Week For Week 13 |
| 2021-12-09 | Hard Knocks In Season Episode 4 Recap: T.Y. Hilton's Leadership Shines As Colts Shut Out Texans |
| 2021-12-09 | Colts DT DeForest Buckner Nominated For 2021 Art Rooney Sportsmanship Award |
| 2021-12-09 | Colts, Kicking The Stigma Encourage Fans To Use Bye Week To Focus On Mental Health |
| 2021-12-13 | NFL Playoffs Scenarios: Colts Enter Week 15 As AFC No. 6 Seed |
| 2021-12-13 | Colts Release Unofficial Depth Chart For Week 15 Game vs. New England Patriots |
| 2021-12-13 | Kenny Moore II On Being Named Colts' Walter Payton Man Of The Year Nominee: 'It means a lot to me' |
| 2021-12-14 | How to Watch: Patriots @ Colts |
| 2021-12-14 | Colts Activate Ryan Kelly From Reserve/COVID-19 List |
| 2021-12-14 | Colts Name Centerville's Memphis Lee As 'High School Man Of The Year' |
| 2021-12-14 | Adam Vinatieri: Colts vs. Patriots Is 'Going To Feel Like A Playoff Game' |
| 2021-12-14 | Colts Daily Notebook: Patriots Bringing 'Big Boy Football' To Lucas Oil Stadium, Literally And Figuratively |
| 2021-12-15 | Colts Activate LB Malik Jefferson To 53-Man Roster From Practice Squad, Sign S Will Redmond To Practice Squad |
| 2021-12-15 | Colts Daily Notebook: Ex-Patriot Kenny Moore II Viewing Saturday's Showdown Just Like Any Other Game |
| 2021-12-16 | Hard Knocks In Season Episode 5 Recap: Inside Colts' Mental, Physical Break During Bye Week |
| 2021-12-16 | Colts To Host Patriots For 'Primetime Saturday Night' In Indy |
| 2021-12-16 | Colts Week 17 Game vs. Las Vegas Raiders To Be Televised On FOX |
| 2021-12-16 | Colts Mailbag: AFC Playoff Odds And Scenarios, Bill Belichick's Patriots Defense, Jonathan Taylor's Shot At NFL MVP |
| 2021-12-16 | Colts Rule Out DT Antwaun Woods For Week 15 vs. New England Patriots |
| 2021-12-17 | Why 'Mr. Reliable' Jack Doyle Is Still An X-Factor In Year 9 With Colts |
| 2021-12-17 | 5 Things To Watch: Colts vs. Patriots, Week 15 |
| 2021-12-18 | 2021 Colts Fantasy Preview: Colts vs. Patriots, Week 15 |
| 2021-12-18 | Colts Activate LB Zaire Franklin From Reserve/COVID-19 List, Elevate DT Chris Williams To Active Roster From Practice Squad, Place DT Antwaun Woods On Injured Reserve |
| 2021-12-18 | Colts Announce Six Inactive Players For Week 15 vs. New England Patriots |
| 2021-12-19 | LIVE BLOG, Colts vs Patriots Week 15 |
| 2021-12-19 | Opportunistic Colts Defense Shuts Down Patriots For Three Quarters, Puts Clamps Down Late |
| 2021-12-19 | By The Numbers: Colts 27, Patriots 17 (2021 Week 15) |
| 2021-12-19 | Colts' Strengthen Grip On AFC Playoff Spot With Win Over Patriots But Aren't Done Yet: 'This Counts For One, That's It' |
| 2021-12-19 | Colts' Jonathan Taylor Rushing Into NFL MVP Conversation After Win Over Patriots |
| 2021-12-19 | Yet Another Blocked Punt, Special Teams Touchdown Sets Tone For Colts In Huge Win Over Patriots |
| 2021-12-20 | 5 Things Learned: Colts vs. Patriots, Week 15 |
| 2021-12-20 | Colts' Jonathan Taylor Nominated For Week 15 FedEx Air & Ground Player Of The Week |
| 2021-12-20 | Colts Release Unofficial Depth Chart For Week 16 Game vs. Arizona Cardinals |
| 2021-12-20 | Colts RB Jonathan Taylor Selected To 2022 Pro Bowl |
| 2021-12-21 | NFL Playoffs Scenarios: Colts Enter Week 16 As AFC No. 5 Seed; Door Still Open To Win AFC South |
| 2021-12-21 | Colts Sign DT Da’Shawn Hand To Practice Squad, Release CB Darqueze Dennard From Practice Squad |
| 2021-12-21 | How to Watch: Colts @ Cardinals |
| 2021-12-21 | Colts Select T.Y. Hilton As Recipient Of The 2021 Ed Block Courage Award |
| 2021-12-21 | Colts Daily Notebook: Carson Wentz's Role In Run Game Goes Beyond Handing Off To Jonathan Taylor |
| 2021-12-22 | Colts LB Darius Leonard Named AFC Defensive Player Of The Week For Week 15 |
| 2021-12-22 | Colts Daily Notebook: Kenny Moore II Keeps Making Plays As Quarterbacks Keep Throwing At Him |
| 2021-12-22 | Colts RB Jonathan Taylor Named FedEx Ground Player of the Week For Week 15 |
| 2021-12-23 | Seven Colts Players Named To 2022 Pro Bowl |
| 2021-12-23 | Hard Knocks In Season Episode 6 Recap: Behind The Scenes For Colts' Big, Emotional Win Over Patriots |
| 2021-12-23 | Colts Mailbag: AFC South & Playoff Tiebreakers, Kyler Murray, Michael Badgley, Parris Campbell |
| 2021-12-23 | Colts Place G Mark Glowinski On Reserve/COVID-19 List, Rule Out C Ryan Kelly For Week 16 vs. Arizona Cardinals |
| 2021-12-23 | 5 Things To Watch: Colts vs. Cardinals, Week 16 |
| 2021-12-23 | Six Colts Players Named 2022 Pro Bowl Alternates |
| 2021-12-24 | 2021 Colts Fantasy Preview: Colts vs. Cardinals, Week 16 |
| 2021-12-25 | Colts Elevate 6 Players To Active Roster From Practice Squad As COVID-19 Replacements, Place 3 Players On Reserve/COVID-19 List |
| 2021-12-25 | Colts Announce 4 Inactive Players For Week 16 vs. Arizona Cardinals |
| 2021-12-26 | LIVE BLOG, Colts vs. Cardinals Week 16 |
| 2021-12-26 | Colts’ Defense Stifles Kyler Murray, Cardinals’ Offense Despite Major Missing Pieces |
| 2021-12-26 | Colts Overcome Adversity To Beat Cardinals, Move Closer To Spot In AFC Playoffs |
| 2021-12-26 | With Colts In Playoff Mode, Carson Wentz Steps Up In Win Over Cardinals |
| 2021-12-26 | By The Numbers: Colts 22, Cardinals 16 (2021 Week 16) |
| 2021-12-27 | 5 Things Learned: Colts vs. Cardinals, Week 16 |
| 2021-12-27 | Frank Reich Shares Message To Colts as 6 More Players Placed On COVID List |
| 2021-12-28 | Colts Can Clinch AFC Playoff Spot With Win Over Las Vegas Raiders In Week 17 |
| 2021-12-28 | Why Colts Are, And Have Been, Confident In Sam Ehlinger As Backup Quarterback |
| 2021-12-28 | Colts Sign C Joey Hunt, Activate T Greg Senat To 53-Man Roster From Practice Squad, Sign S D.J. Swearinger To Practice Squad |
| 2021-12-28 | Colts Release Unofficial Depth Chart For Week 17 Game vs. Las Vegas Raiders |
| 2021-12-29 | How to Watch: Raiders @ Colts |
| 2021-12-29 | Colts Activate 5 Players From Reserve/COVID-19 List After NFL, NFLPA Update Isolation Protocols |
| 2021-12-29 | Daily Notebook: Whether Carson Wentz Or Sam Ehlinger Starts, Colts Confident In Quarterback Situation vs. Las Vegas Raiders |
| 2021-12-30 | Hard Knocks In Season Episode 7 Recap: Colts Weather COVID Storm To Beat Cardinals On Christmas |
| 2021-12-30 | Colts Activate Darius Leonard, Zach Pascal, Khari Willis From Reserve/COVID-19 List |
| 2021-12-30 | How T.Y. Hilton Is Making A Massive Impact On Colts On And Off The Field: 'He Knows The Pulse Of The Team' |
| 2021-12-30 | Team To Celebrate Colts Nation At 'Fan Appreciation Game' On January 2 |
| 2021-12-30 | Colts Mailbag: AFC Playoff Scenarios & Potential Opponents, Parris Campbell's Return, Jonathan Taylor's MVP Odds |
| 2021-12-30 | Ryan Kelly's Statement On Loss, Grief And Thankfulness |
| 2021-12-30 | Daily Notebook: How Colts' Training Camp Is Paying Off Late In 2021 Season |
| 2021-12-30 | Reggie Wayne Named Finalist For Pro Football Hall Of Fame Class Of 2022 |
| 2021-12-31 | Colts Activate S Jahleel Addae, RB Marlon Mack From Reserve/COVID-19 List |
| 2021-12-31 | Colts Place LS Luke Rhodes On Reserve/COVID-19 List, Sign LS Kyle Nelson To Practice Squad, Release DT Da'Shawn Hand From Practice Squad |
| 2021-12-31 | Colts Rule Out S Andrew Sendejo For Week 17 vs. Las Vegas Raiders |
| 2021-12-31 | 5 Things To Watch: Colts vs. Raiders, Week 17 |
