| 2022-01-01 | Colts Activate 3 From Reserve/COVID-19 List, Activate 4 From Practice Squad Ahead Of Week 17 Game Against Las Vegas Raiders |
| 2022-01-02 | 2021 Colts Fantasy Preview: Colts vs. Raiders, Week 17 |
| 2022-01-02 | Colts Announce Seven Inactive Players For Week 17 vs. Las Vegas Raiders |
| 2022-01-02 | LIVE BLOG, Colts vs. Raiders Week 17 |
| 2022-01-02 | By The Numbers: Raiders 23, Colts 20 (2021 Week 17) |
| 2022-01-02 | Jonathan Taylor Becomes Colts’ Single-Season Rushing Yards King |
| 2022-01-03 | Colts Still Control AFC Playoff Destiny But Exit Week 17 Disappointed In Loss To Las Vegas Raiders |
| 2022-01-03 | 5 Things Learned: Colts vs. Raiders, Week 17 |
| 2022-01-03 | Colts Activate Malik Jefferson From Reserve/COVID-19 List, Restore James Morgan, Eli Wolf To Practice Squad, Release Kyle Nelson From Practice Squad |
| 2022-01-04 | 2021 Week 18 NFL Playoff Picture: Colts Clinching, Seeding Scenarios |
| 2022-01-04 | Colts Waive LB Malik Jefferson |
| 2022-01-04 | Colts Sign T Shon Coleman To Practice Squad |
| 2022-01-05 | Colts Release Unofficial Depth Chart For Week 18 Game vs. Jacksonville Jaguars |
| 2022-01-05 | Colts Activate LS Luke Rhodes From Reserve/COVID-19 List |
| 2022-01-05 | How to Watch: Colts @ Jaguars |
| 2022-01-05 | Daily Notebook: Colts Expecting Jaguars' Best Effort In Week 18 |
| 2022-01-06 | Hard Knocks In Season Episode 9 Recap: The End Of The Climb |
| 2022-01-06 | 5 Reasons Why Colts' Jonathan Taylor Earned His Way Into 2021 NFL MVP Conversation |
| 2022-01-06 | Daily Notebook: 317 Rushing Attempts Into 2021 Season, Jonathan Taylor Still Feels 'Great' |
| 2022-01-07 | Colts Mailbag: Most Likely AFC Playoffs Wild Card Round Opponent, 2022 NFL Draft, Rock Ya-Sin's Strong Season |
| 2022-01-07 | Colts Rule CB Xavier Rhodes Out For Week 18 vs. Jacksonville Jaguars |
| 2022-01-07 | 5 Things To Watch: Colts vs. Jaguars, Week 18 |
| 2022-01-08 | Colts Activate WR Parris Campbell From Injured Reserve, Elevate CB Anthony Chesley, S Will Redmond, DT Chris Williams To Active Roster From Practice Squad |
| 2022-01-09 | Colts Announce 7 Inactive Players For Week 18 vs. Jacksonville Jaguars |
| 2022-01-09 | LIVE BLOG, Colts vs. Jaguars Week 18 |
| 2022-01-09 | By The Numbers: Jaguars 26, Colts 11 (2021 Week 18) |
| 2022-01-09 | Colts Eliminated From 2021 NFL Playoffs With Loss To Jaguars That Will 'Hurt For A Long Time' |
| 2022-01-10 | Colts' 2022 NFL Regular Season Opponents Finalized |
| 2022-01-10 | 5 Things Learned: Colts vs. Jaguars, Week 18 |
| 2022-01-10 | Colts Sign 14 Players To Reserve/Future Contracts |
| 2022-01-10 | Colts Head Coach Frank Reich On 'Scar' Of End To 2021 Season: 'We’re Going To Learn From It And Get Better' |
| 2022-01-12 | Colts' T.Y. Hilton, Jack Doyle Will Take Time To Decide What's Next |
| 2022-01-12 | TUNE IN: Chris Ballard’s End of Season Press Conference Thursday at Noon ET |
| 2022-01-12 | Colts Sign CB Alexander Myres To Reserve/Future Contract |
| 2022-01-13 | Hard Knocks In Season Episode 9 Recap: The End Of The Climb |
| 2022-01-13 | Colts RB Jonathan Taylor Nominated For 2021 FedEx Ground Player of the Year |
| 2022-01-13 | Top Takeaways: Chris Ballard's End-Of-Season Press Conference |
| 2022-01-14 | Colts' Darius Leonard, Luke Rhodes, Jonathan Taylor Named 2021 First-Team AP All-Pros |
| 2022-01-18 | Important NFL 2022 Offseason Dates |
| 2022-01-18 | Four Colts Players Named To Pro Football Focus' 2021 All-Pro Team |
| 2022-01-19 | How Jeff Saturday Sees Colts Moving On From Sting Of Missing Playoffs In 2021 Season |
| 2022-01-20 | Colts GM Chris Ballard Discusses Quarterbacks, Jonathan Taylor, Ed Dodds & Morocco Brown |
| 2022-01-20 | Colts Sign OT Jordan Murray To Reserve/Future Contract |
| 2022-01-24 | Jonathan Taylor, Darius Leonard, Quenton Nelson Earn Spots On PFWA All-NFL, All-AFC Teams |
| 2022-01-25 | Colts 2022 Pro Bowl Spotlight: DeForest Buckner |
| 2022-01-25 | Colts DE Kwity Paye Named To PFWA All-Rookie Team |
| 2022-01-26 | Colts 2022 Pro Bowl Spotlight: Ryan Kelly |
| 2022-01-26 | Colts Sign TE Nikola Kalinic To Reserve/Future Contract |
| 2022-01-27 | Colts 2022 Pro Bowl Spotlight: Darius Leonard |
| 2022-01-28 | Matt Eberflus Hired As Chicago Bears Head Coach |
| 2022-01-28 | Colts 2022 Pro Bowl Spotlight: Kenny Moore II |
| 2022-01-31 | Colts 2022 Pro Bowl Spotlight: Quenton Nelson |
