Running back Marlon Mack bursts through the middle on 20-yard dash.

Guard Quenton Nelson's block helps spring running back Marlon Mack's 24-yard run.

Watch the highlights from the Week 8 matchup between the Denver Broncos and the Indianapolis Colts.

Indianapolis Colts running back Marlon Mack on his performance in the team's come from behind victory over the Denver Broncos.

Running back Marlon Mack rushes for a 10-yard touchdown vs. the Denver Broncos.

Indianapolis Colts running back Marlon Mack shares his great appreciation for the team's offensive line and how much it helps having a unit that has been together for over a season.

Indianapolis Colts running back Marlon Mack discusses what he is doing to make sure that the team can carry the momentum they got from Kansas City and how important the bye week is to the team's health.

Indianapolis Colts running back Marlon Mack talks about how it felt to earn a victory over the previously undefeated Kansas City Chiefs on Sunday Night Football.

Runnning back Marlon Mack follows blockers for key fourth-down conversion.

Running back Marlon Mack muscles through would-be tacklers for 30 yards.

Indianapolis Colts running back Marlon Mack discusses his late touchdown to help seal the team's 27-24 victory over the Atlanta Falcons.

Indianapolis Colts running back Marlon Mack makes 26-yard run.

Running back Marlon Mack rushes for a 4-yard touchdown.

Indianapolis Colts running back Marlon Mack described how his role changes each game based on what the team needs and how the offensive line allows him to play at a high level.

Running back Marlon Mack powers in for game-tying two-point conversion late.

Running back Marlon Mack burns Chargers on blazing fast 63-yard touchdown.

Running back Marlon Mack weaves through Chargers defense to start second half.

Indianapolis Colts running back Marlon Mack discusses his off-season, preparing for the 2019 season and more as the team enters phase 2 of their off-season program.

Marlon Mack runs for 20 yards.

NFL Network's Nate Burleson breaks down Indianapolis Colts running back Marlon Mack's career day against the Houston Texans in the AFC Wild Card Game.

The stats suggest the Colts should look to get the run game going early at Arrowhead. Colts reporter Caroline Cann breaks down the storylines heading into the Colts' matchup with the Kansas City Chiefs, including notable stats to be aware of entering the Divisional Round playoff matchup.

Indianapolis Colts running back Marlon Mack shifts his way into the end zone on a 2-yard carry.

Indianapolis Colts running back Marlon Mack breaks through for a big 25-yard pickup behind solid blocking from his O-line.

Watch the best plays from Indianapolis Colts running back Marlon Mack's 154-yard day against the Houston Texans in the AFC Wild Card.

Go inside the helmet of Indianapolis Colts running back Marlon Mack on a 29-yard run against the Houston Texans in the Wild Card round.

At 5-3 heading into Sunday’s Week 10 matchup against the Miami Dolphins, the Indianapolis Colts have reached the midpoint of the 2019 season. Here’s a comprehensive look back at the Colts' performance from a fantasy football perspective.

A potentially huge fantasy matchup awaits the Indianapolis Colts this Sunday as they host the Miami Dolphins. Here's what to expect from the Colts players on your fantasy rosters in Week 10.

The Indianapolis Colts have announced their inactives list for tonight’s Week 5 matchup against the Kansas City Chiefs, and among those who were questionable heading in who are active include top wide receiver T.Y. Hilton and running back Marlon Mack.

Indianapolis Colts head coach Frank Reich today announced that five players — wide receiver Parris Campbell, safety Clayton Geathers, safety Malik Hooker, linebacker Darius Leonard and defensive tackle/end Tyquan Lewis — have been ruled out for Sunday's Week 5 matchup against the Kansas City Chiefs. Five other players are questionable for the game.

Indianapolis Colts head coach Frank Reich said Monday that safety Clayton Geathers developed concussion symptoms after Sunday’s loss to the Oakland Raiders, and has been placed in the league’s concussion protocol.

The Indianapolis Colts on Thursday held their second of three practices as they prepare for Sunday’s 2019 home opener against the Atlanta Falcons. What all did we learn on the day?

Fresh off his career day against the Los Angeles Chargers, Indianapolis Colts running back Marlon Mack was voted by fans as the NFL’s FedEx Ground Player of the Week.

The Indianapolis Colts may have lost their regular season opener to the Los Angeles Chargers on Sunday, but several of their players earned high marks in the effort according to Pro Football Focus, including running back Marlon Mack, who was named to PFF's Week 1 "Team of the Week."

Indianapolis Colts running back Marlon Mack put in a career day in Sunday’s season-opening loss to the Los Angeles Chargers, running for 174 yards and a touchdown. Now it’s time to vote for Mack for the Week 1 FedExGround Player of the Week Award.

Indianapolis Colts running back Marlon Mack ran for a career-high 174 yards in the team's Week 1 overtime loss to the Los Angeles Chargers on Sunday.

Returning for practice on Monday, the Indianapolis Colts' players reacted to the sudden retirement of teammate Andrew Luck, who announced his decision Saturday night.

With the Indianapolis Colts set to begin training camp soon at Grand Park Sports Campus in Westfield, Ind., Colts.com previews the team’s running backs.

Examining the fantasy football prospects for the primary Indianapolis Colts players heading into the 2019 season.

With the 2019 regular season right around the corner, what are some milestones for the Indianapolis Colts and their players to keep an eye on?

Take a look at the burning questions at each position as the Indianapolis Colts get set to report to training camp July 24 at Grand Park Sports Campus in Westfield, Ind. We continue today with the running back position.

According to NFL.com senior fantasy analyst Michael Fabiano, Indianapolis Colts running back Marlon Mack should be considered a fantasy football winner following the league’s big wave of free agency.

The Houston Texans went the entire 2018 regular season without allowing a 100-yard rusher. Marlon Mack took care of that in Saturday’s Wild Card Round matchup, however, as the Indianapolis Colts set playoff records for total rushing yards, and Mack ran for the most yards in Colts postseason history.

The Indianapolis Colts’ 2018 Week 15 Drive of the Game, presented by Hays + Sons, was an eight-play, 44-yard sequence midway through the first quarter that gave the Colts an early 7-0 lead they’d never relinquish in their shutout victory over the Dallas Cowboys.

Indianapolis Colts running back Marlon Mack is up for FedEx Ground Player of the Week and defensive lineman Tyquan Lewis is a nominee for Rookie of the Week after the pair’s performance in the Colts’ 23-0 victory over the Dallas Cowboys in Week 15.

Indianapolis Colts running back Marlon Mack ran for a career-high 139 yards on 27 carries in the Colts’ 23-0 win over the Dallas Cowboys on Sunday.

Marlon Mack, who was in the league’s concussion protocol, was not on the team’s inactives list for today’s Week 13 matchup against the Jacksonville Jaguars, paving the way for the Indianapolis Colts to have their top running back in the lineup.

Indianapolis Colts running back Marlon Mack, in the concussion protocol after being knocked out of last Sunday’s Week 12 matchup against the Miami Dolphins, made his return to the practice field on Thursday. He was one of a few key playmakers to return after missing Wednesday’s practice.

Indianapolis Colts running back Marlon Mack (FedEx Ground Player of the Week) and linebacker Darius Leonard (NFL Rookie of the Week) are, for a second straight week, nominees for weekly league awards. Go vote now, and vote often.

The Indianapolis Colts dominated play on the ground for a second straight week, as running backs Marlon Mack and Nyheim Hines combined for 210 rushing yards in Indy's 42-28 victory over the Bills.

For their efforts against the Buffalo Bills in Week 7, Indianapolis Colts running back Marlon Mack and linebacker Darius Leonard are up for a couple of weekly NFL awards.