Watch running back Marlon Mack's best plays from 2-TD game in Week 17.

Indianapolis Colts running back Marlon Mack describes his strong performance and the play of the team's offensive line following their week 17 loss to the Jacksonville Jaguars.

Wide receiver Zach Pascal's great block helps spring running back Marlon Mack score second touchdown.

Running back Marlon Mack finds a spot to rush in for a 5-yard touchdown.

Running back Marlon Mack shows tremendous vision with a patient 30-yard burst.

Offensive line paves the way for Colts running back Marlon Mack's touchdown run.

Running back Marlon Mack powers through for touchdown in his return back to Colts' lineup.

Running back Marlon Mack run for 109 yards, including 83 in the first half in Week 11 against the Jacksonville Jaguars. Here are his best plays.

Running backs Jonathan Williams and Marlon Mack each gained 100 yards on the ground in Week 11 against the Jaguars. It's a franchise first for the Colts to have two 100-yard rushers in the same game.

Running back Marlon Mack finds the end zone by breaking tackles through the Jacksonville Jaguars defense and pulling off a pair of slick spin moves in Week 11.

Running back Marlon Mack bursts through the middle on 20-yard dash.

Guard Quenton Nelson's block helps spring running back Marlon Mack's 24-yard run.

Watch the highlights from the Week 8 matchup between the Denver Broncos and the Indianapolis Colts.

Indianapolis Colts running back Marlon Mack on his performance in the team's come from behind victory over the Denver Broncos.

Running back Marlon Mack rushes for a 10-yard touchdown vs. the Denver Broncos.

Indianapolis Colts running back Marlon Mack shares his great appreciation for the team's offensive line and how much it helps having a unit that has been together for over a season.

Indianapolis Colts running back Marlon Mack discusses what he is doing to make sure that the team can carry the momentum they got from Kansas City and how important the bye week is to the team's health.

Indianapolis Colts running back Marlon Mack talks about how it felt to earn a victory over the previously undefeated Kansas City Chiefs on Sunday Night Football.

Runnning back Marlon Mack follows blockers for key fourth-down conversion.

Running back Marlon Mack muscles through would-be tacklers for 30 yards.

Indianapolis Colts running back Marlon Mack discusses his late touchdown to help seal the team's 27-24 victory over the Atlanta Falcons.

Indianapolis Colts running back Marlon Mack makes 26-yard run.

Running back Marlon Mack rushes for a 4-yard touchdown.

Indianapolis Colts running back Marlon Mack described how his role changes each game based on what the team needs and how the offensive line allows him to play at a high level.

Running back Marlon Mack powers in for game-tying two-point conversion late.

The Indianapolis Colts and their dominant run game travel south to take on the Jacksonville Jaguars this Sunday. The Colts had over 250 rushing yards the last time these teams played in November. What might this week look like for your fantasy football lineups?

The Indianapolis Colts were all over Pro Football Focus' 'NFL Week 16 Team of the Week' and had several other players near the top of their respective positional rankings after the team defeated the Carolina Panthers, 38-6, on Sunday in Indy.

With 16 rushing attempts for 95 yards and a touchdown in Sunday's Week 16 victory over the Carolina Panthers, third-year Indianapolis Colts running back Marlon Mack eclipsed 1,000 rushing yards on the year for the first time in his career.

The Indianapolis Colts could provide some firepower for your fantasy football rosters this week in the championship round. Let's take a look at the matchup they have ahead on Sunday with the Carolina Panthers.

The Indianapolis Colts had two players selected to play in the 2020 Pro Bowl, but seven others were selected as alternates — five on offense, one on defense and one on special teams.

The Indianapolis Colts take on the New Orleans Saints this week at the Mercedes-Benz Superdome to help decide whether or not many of us get to our fantasy football championships. Let's take a look at the matchup they have ahead with the Saints.

The Indianapolis Colts today held their first of three practices to prepare for Monday night's Week 15 matchup against the New Orleans Saints. What all did we learn on the day?

The Indianapolis Colts' offense should be getting a much-needed shot in the arm today against the Tampa Bay Buccaneers, as wide receiver Parris Campbell and top running back Marlon Mack are expected to return after missing multiple games with injuries.

The Indianapolis Colts take on the Tampa Bay Buccaneers this weekend in a matchup that could create some explosive fantasy performances. Here's what to expect from the Colts players on your fantasy rosters in Week 14 against the Buccaneers.

Indianapolis Colts head coach Frank Reich announced today that three players — wide receiver T.Y. Hilton, cornerback Kenny Moore II and kicker Adam Vinatieri — have been ruled out for Sunday's Week 14 matchup against the Tampa Bay Buccaneers. Wide receiver Parris Campbell and running back Marlon Mack are expected to play, meanwhile.

The Indianapolis Colts on Thursday held their second of three days of practice to prepare for Sunday's Week 14 road matchup against the Tampa Bay Buccaneers. What all did we learn on the day?

The Indianapolis Colts on Wednesday held their first of three days of practice to get ready for Sunday's Week 14 road contest against the Tampa Bay Buccaneers. What all did we learn on the day?

Indianapolis Colts head coach Frank Reich today said wide receiver Chester Rogers, who suffered a knee injury in Sunday's loss to the Tennessee Titans, will be placed on injured reserve, ending his season. He also had updates on wide receivers Parris Campbell and T.Y. Hilton, as well as running back Marlon Mack.

Indianapolis Colts head coach Frank Reich announced today that wide receiver T.Y. Hilton and running back Marlon Mack have been ruled out of Sunday's Week 13 matchup against the Tennessee Titans. Four other Colts players, meanwhile, are questionable.

Indianapolis Colts head coach Frank Reich on Monday held a conference call with local reporters, in which he discussed putting tight end Eric Ebron on injured reserve, signing tight end Ross Travis and injury updates for wide receivers T.Y. Hilton, Devin Funchess, Parris Campbell and running back Marlon Mack.

For the second time this season, Indianapolis Colts running back Marlon Mack has been voted the NFL's FedEx Ground Player of the Week, this most recent award coming off the heels of a standout performance in the Colts' Week 11 win over the Jacksonville Jaguars.

The Indianapolis Colts announced today that four players — wide receiver Parris Campbell, running back Marlon Mack, cornerback Shakial Taylor and safety Khari Willis — have been ruled out of Thursday night's game against the Houston Texans. Four other players, meanwhile, are questionable.

Indianapolis Colts running back Marlon Mack (FedEx Ground Player of the Week) and cornerback Marvell Tell III (Rookie of the Week) are up for a couple NFL weekly awards. Now it's up to Colts Nation to ensure they come away with the hardware.

The Indianapolis Colts earned their most dominant victory of the season on Sunday when they defeated the Jacksonville Jaguars at home, 33-13. Pro Football Focus recognized several of their players with high-quality grades, even placing left guard Quenton Nelson and running back Jonathan Williams on their Week 11 "Team of the Week."

Indianapolis Colts head coach Frank Reich said today that running back Marlon Mack (hand) and safety Khari Willis (concussion) have both already been ruled out of Thursday night's Week 12 matchup against the Houston Texans.

The Indianapolis Colts won't have much time to celebrate a huge Week 11 victory over the Jacksonville Jaguars, as getting healthy for their massive Thursday Night Football matchup against the Houston Texans instantly becomes priority No. 1.

The Indianapolis Colts ran for 264 yards in their 33-13 victory over the Jacksonville Jaguars on Sunday, their highest total since 2004. They also had two 100-yard rushers in a single game for the first time since 1985.

What does the likely return of their quarterback mean for the Indianapolis Colts this weekend against the Jacksonville Jaguars from a fantasy football perspective? Here's what to expect from the Colts players on your fantasy rosters in Week 11.

At 5-3 heading into Sunday's Week 10 matchup against the Miami Dolphins, the Indianapolis Colts have reached the midpoint of the 2019 season. Here's a comprehensive look back at the Colts' performance from a fantasy football perspective.

A potentially huge fantasy matchup awaits the Indianapolis Colts this Sunday as they host the Miami Dolphins. Here's what to expect from the Colts players on your fantasy rosters in Week 10.