| 2022-09-01 | Pelissero: Shaquille Leonard returned to practice following offseason back surgery |
| 2022-09-01 | JoJo Domann: Media Availability, September 1 |
| 2022-09-01 | Parris Campbell: Media Availability, September 1 |
| 2022-09-01 | Shaquille Leonard: Media Availability, September 1 |
| 2022-09-01 | Frank Reich: Media Availability, September 1 |
| 2022-09-01 | Tyquan Lewis In Studio |
| 2022-09-04 | Grover Stewart Mic'd Up: Preseason Week 3 vs. Tampa Bay |
| 2022-09-05 | Which team hasn't been talked about enough? 'GMFB' |
| 2022-09-05 | Frank Reich: Media Availability, September 5 |
| 2022-09-06 | DC Gus Bradley: Colts at Texans, Week 1 |
| 2022-09-06 | OC Marcus Brady: Colts at Texans, Week 1 |
| 2022-09-07 | Manning leads Colts to victory in first-ever meeting vs. Texans NFL Throwback |
| 2022-09-07 | Colts vs. Texans preview Week 1 |
| 2022-09-07 | Behind The Colts: Part 3 |
| 2022-09-07 | Matt Ryan: Colts at Texans, Week 1 |
| 2022-09-07 | Frank Reich: Mid-week Update, Colts at Texans |
| 2022-09-08 | Jonathan Taylor: Colts at Texans, Week 1 |
| 2022-09-08 | Shaquille Leonard: Colts at Texans, Week 1 |
| 2022-09-08 | For Committing to Greatness | 2022 Colts Season Trailer |
| 2022-09-09 | Nick Cross In Studio |
| 2022-09-09 | Jim Irsay reveals his favorite moment in franchise history |
| 2022-09-09 | Week 1 Final Update: Frank Reich, Colts at Texans |
| 2022-09-11 | Colts at Texans: Week One Game Preview |
| 2022-09-11 | Pregame With Coach Reich: Colts @ Texans |
| 2022-09-11 | Matt Ryan absorbs Grugier-Hill's hit stick on run for first down |
| 2022-09-11 | Jonathan Taylor follows his blockers on way to 17-yard gain |
| 2022-09-11 | Matt Ryan finds Michael Pittman in wide-open space for 28-yard gain |
| 2022-09-11 | E.J Speed flies off the edge to force sack-fumble |
| 2022-09-11 | Jonathan Taylor powers in 2-yard TD |
| 2022-09-11 | Jonathan Taylor's truck stick works wonders on 13-yard run |
| 2022-09-11 | Can't-Miss Play: Michael Pittman Jr. plows past goal line for PIVOTAL TD |
| 2022-09-11 | Jonathan Taylor's best plays vs. Texans Week 1 |
| 2022-09-11 | Matt Ryan's best plays in Colts debut Week 1 |
| 2022-09-11 | Parris Campbell: Colts at Texans Postgame |
| 2022-09-11 | Kwity Paye: Colts at Texans Postgame |
| 2022-09-11 | Stephon Gilmore: Colts at Texans Postgame |
| 2022-09-11 | Colts vs. Texans highlights Week 1 |
| 2022-09-11 | Colts' top plays vs. Texans Week 1 |
| 2022-09-11 | Matt Ryan: Colts at Texans Postgame |
| 2022-09-11 | Frank Reich: Colts at Texans Postgame |
| 2022-09-12 | Roundtable in Studio: Frank Reich, Colts at Texans |
| 2022-09-12 | Parris Campbell: Media Availability, September 12 |
| 2022-09-12 | Kwity Paye: Media Availability, September 12 |
| 2022-09-12 | Week 1 Recap: Frank Reich, Colts at Texans |
| 2022-09-13 | DC Gus Bradley: Colts at Jaguars, Week 2 |
| 2022-09-13 | STC Bubba Ventrone: Colts at Jaguars, Week 2 |
| 2022-09-13 | OC Marcus Brady: Colts at Jaguars, Week 2 |
| 2022-09-14 | Mic'd Up: Nyheim Hines, Week One In Houston |
| 2022-09-14 | Matt Ryan: Colts at Jaguars, Week 2 |
| 2022-09-14 | Frank Reich: Mid-week Update, Colts at Jaguars |
| 2022-09-15 | Shaquille Leonard: Colts at Jaguars, Week 2 |
| 2022-09-15 | Jonathan Taylor: Colts at Jaguars, Week 2 |
| 2022-09-16 | Colts vs. Jaguars preview Week 2 |
| 2022-09-16 | Week 2 Final Update: Frank Reich, Colts at Jaguars |
| 2022-09-18 | Colts at Jaguars: Week Two Game Preview |
| 2022-09-18 | Pregame With Coach Reich: Colts @ Jaguars |
| 2022-09-18 | HIGHLIGHT | Nyheim Hines finds open space over middle on 19 yard catch and run |
| 2022-09-18 | HIGHLIGHT | Byron Cowart is an absolute FORCE on TFL vs. Etienne |
| 2022-09-18 | HIGHLIGHT | E.J. Speed uses his speed for MASSIVE tackle for loss |
| 2022-09-18 | Can't-Miss Play: Jonathan Taylor casts bid for truck-stick run of year |
| 2022-09-18 | HIGHLIGHT | Stephon Gilmore nearly picks off Trevor Lawrence on high-point pass |
| 2022-09-18 | Can't-Miss Play: Matt Ryan dials launch codes for 39-yard gain to Ashton Dulin |
| 2022-09-18 | Zaire Franklin: Colts at Jaguars Postgame |
| 2022-09-18 | Nyheim Hines: Colts at Jaguars Postgame |
| 2022-09-18 | Matt Ryan: Colts at Jaguars Postgame |
| 2022-09-18 | Frank Reich: Colts at Jaguars Postgame |
| 2022-09-19 | Grover Stewart: Media Availability, September 19 |
| 2022-09-19 | Week 2 Recap: Frank Reich, Colts at Jaguars |
| 2022-09-20 | DC Gus Bradley: Colts vs. Chiefs, Week 3 |
| 2022-09-21 | Matt Ryan: Colts vs. Chiefs, Week 3 |
| 2022-09-21 | Frank Reich: Mid-week Update, Colts vs. Chiefs |
| 2022-09-22 | Shaquille Leonard: Colts vs. Chiefs, Week 3 |
| 2022-09-22 | Jonathan Taylor: Colts vs. Chiefs, Week 3 |
| 2022-09-22 | Zaire Franklin In Studio |
| 2022-09-23 | Chiefs vs. Colts preview Week 3 |
| 2022-09-23 | Week 3 Final Update: Frank Reich, Colts vs. Chiefs |
| 2022-09-23 | Beyond The Sidelines: Kay Adams, Up & Adams Host |
| 2022-09-25 | Colts vs. Chiefs: Week Three Game Preview |
| 2022-09-25 | Pregame With Coach Reich: Colts vs Chiefs |
| 2022-09-25 | HIGHLIGHT | Kylen Granson recovers Skyy Moore's muffed punt inside Chiefs' 10-yard line |
| 2022-09-25 | HIGHLIGHT | Jelani Woods' first career TD catch comes after fellow rookie Skyy Moore's muffed punt |
| 2022-09-25 | HIGHLIGHT | Colts pin Chiefs inside KC's 1-yard line on perfect punt |
| 2022-09-25 | HIGHLIGHT | Matt Ryan lasers 17-yard pass to Alec Pierce over middle |
| 2022-09-25 | HIGHLIGHT | Michael Pittman Jr. rips away potential INT, translates it into 25-yard gain |
| 2022-09-25 | Can't-Miss Play: Matt Ryan delivers go-ahead TD to Woods with under 0:30 remaining |
| 2022-09-25 | Can't-Miss Play: Rodney McLeod ICES Colts' win over Chiefs with INT on Mahomes |
| 2022-09-25 | Matt Ryan: Best Plays vs. Chiefs, Week 3 |
| 2022-09-25 | Chiefs vs. Colts Highlights, Week 3 |
| 2022-09-25 | Matt Ryan discusses importance of Colts' win over Chiefs in Week 3 |
| 2022-09-25 | Colts' Top Plays vs. Chiefs, Week 3 |
| 2022-09-25 | Alec Pierce: Colts vs. Chiefs Postgame |
| 2022-09-25 | Stephon Gilmore: Colts vs. Chiefs Postgame |
| 2022-09-25 | Jelani Woods: Colts vs. Chiefs Postgame |
| 2022-09-25 | Matt Ryan: Colts vs. Chiefs Postgame |
| 2022-09-25 | Frank Reich: Colts vs. Chiefs Postgame |
| 2022-09-26 | Victory Speech: Colts vs. Chiefs |
| 2022-09-26 | 'GMFB' awards Week 3 game balls |
| 2022-09-26 | Palmer: What Colts defense did to catch Chiefs 'off guard' in Week 3 |
| 2022-09-26 | Alec Pierce: Media Availability, September 26 |
| 2022-09-26 | Week 3 Recap: Frank Reich, Colts vs. Chiefs |
| 2022-09-26 | Sights and Sounds: Final Moments of Colts vs Chiefs |
| 2022-09-27 | OC Marcus Brady: Colts vs. Titans, Week 4 |
| 2022-09-27 | DC Gus Bradley: Colts vs. Titans, Week 4 |
| 2022-09-27 | Mic'd Up: Zaire Franklin, Week Three vs. Kansas City |
| 2022-09-28 | Colts vs. Chiefs Game Recap: A Home Thriller |
| 2022-09-28 | Matt Ryan: Colts vs. Titans, Week 4 |
| 2022-09-28 | Frank Reich: Mid-week Update, Colts vs. Titans |
| 2022-09-29 | Shaquille Leonard: Colts vs. Titans, Week 4 |
| 2022-09-29 | Jonathan Taylor: Colts vs. Titans, Week 4 |
| 2022-09-29 | COMING SOON: Colts Declassified: CHUCKSTRONG |
| 2022-09-29 | Titans vs. Colts preview Week 4 |
| 2022-09-30 | Week 4 Final Update: Frank Reich, Colts vs. Titans |
