Indianapolis Colts vs. San Francisco 49ers | Game Center

Colts vs. 49ers | Week 16 Game Center

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San Francisco 49ers 11-4

Indianapolis Colts 8-7

Capitol Ave southbound closure through 2026 will affect all remaining Indianapolis Colts games at Lucas Oil Stadium.

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GAMEDAY ALERT: Road closures and delays expected for Colts fans

Capitol Ave southbound closure through 2026 will affect all remaining Indianapolis Colts games at Lucas Oil Stadium.

Colts Ring of Honor wide receiver Bill Brooks looks at the impressive performances by Philip Rivers and Alec Pierce against the 49ers and what their connection means for the Colts, and offers his perspective on the team's mentality in the final two weeks of the regular season.

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Bill Brooks' Breakdown: Looking at Philip Rivers and Alec Pierce's prime time performances in Week 16

Colts Ring of Honor wide receiver Bill Brooks looks at the impressive performances by Philip Rivers and Alec Pierce against the 49ers and what their connection means for the Colts, and offers his perspective on the team's mentality in the final two weeks of the regular season.

Inside Football with Rick Venturi comes back this week and Matt Taylor and Rick Venturi talk about loss and this one coming to the 49ers in what ended up being not close (3:25) Rick Venturi talks about the challenge in the locker room knowing the final 2 games need to be played but the outcome of reaching the playoffs are out of the Colts hands (13:51) Venturi looks at this Jacksonville turnaround in 2025 and dives into why they have had a 6-game winning streak (17:55) Also, Rick dives in to the blueprints for the Colts defensively to try and defeat the red hot offense in Jacksonville, starting with Trevor Lawrence (28:36) Rick gives his blueprints for the Colts offense on how to try and get Jonathan Taylor back involved against the best rush defense in the NFL (36:18) And finally, Venturi gives his final instruction to the team to get a pivotal victory against the Jaguars in a "must win game" (44:45)

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Overcoming Another Tough Loss and Getting Back on Track Against Jaguars | Inside Football with Rick Venturi

Inside Football with Rick Venturi comes back this week and Matt Taylor and Rick Venturi talk about loss and this one coming to the 49ers in what ended up being not close (3:25) Rick Venturi talks about the challenge in the locker room knowing the final 2 games need to be played but the outcome of reaching the playoffs are out of the Colts hands (13:51) Venturi looks at this Jacksonville turnaround in 2025 and dives into why they have had a 6-game winning streak (17:55) Also, Rick dives in to the blueprints for the Colts defensively to try and defeat the red hot offense in Jacksonville, starting with Trevor Lawrence (28:36) Rick gives his blueprints for the Colts offense on how to try and get Jonathan Taylor back involved against the best rush defense in the NFL (36:18) And finally, Venturi gives his final instruction to the team to get a pivotal victory against the Jaguars in a "must win game" (44:45)

Indianapolis Colts vs. San Francisco 49ers | Game Center

Colts vs. 49ers | Week 16 Game Center

GAMEDAY ALERT: Road closures and delays expected for Colts fans

Bill Brooks' Breakdown: Looking at Philip Rivers and Alec Pierce's prime time performances in Week 16

Overcoming Another Tough Loss and Getting Back on Track Against Jaguars | Inside Football with Rick Venturi

Week 16 Recap: Jim Bob Cooter, Colts vs. 49ers

Game Highlights

49ers vs. Colts highlights Week 16

Philip Rivers' best throws from 277-yard, 2-TD game vs. 49ers Week 16

HIGHLIGHT | Rivers chucks a 33-yard pass to Alec Pierce entry into 49ers' territory

HIGHLIGHT | Camryn Bynum intercepts the Brock Purdy pass vs. San Francisco 49ers

HIGHLIGHT | Philip Rivers lofts a 19-yard pass to Warren en route to the sideline

HIGHLIGHT | Jonathan Taylor's 17th TD run of 2025 trims 49ers' lead to 34-26 in fourth quarter

HIGHLIGHT | Blake Grupe drills a 51-yard FG vs. San Francisco

HIGHLIGHT | Blake Grupe's 39-yard FG trims 49ers' lead to 24-17 just before halftime

HIGHLIGHT | Philip Rivers' 17-yard dart to Pierce has Colts creeping up on the red zone

HIGHLIGHT | Philip Rivers with a 16-yard touchdown pass to Alec Pierce vs. San Francisco 49ers

Can't-Miss Play: Let it fly, Philip! Rivers uncorks 20-yard TD pass to Pierce on first drive vs. 49ers

HIGHLIGHT | Rivers lasers a 17-yard pass to wide-open Josh Downs entering Niners territory

HIGHLIGHT | Rivers-Taylor connections opens up 'MNF' with 19-yard gain vs. 49ers

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