» 2019 Texans record: 10-6 (first place, AFC South)
» 2020 Texans additions: WR Randall Cobb, WR Brandin Cooks, CB Phillip Gaines, CB Vernon Hargreaves III, DT Timmy Jernigan, RB David Johnson, S Eric Murray, T Brent Qvale, DB Jaylen Watkins
» 2020 Texans losses: WR DeAndre Hopkins, RB Carlos Hyde, RB Lamar Miller, DT D.J. Reader, LB Barkevious Mingo, CB Johnathan Joseph, S Jahleel Addae, S Mike Adams, S Tashaun Gipson
» 2020 Texans draft class: DT Ross Blacklock, Edge Jonathan Greenard, T Charlie Heck, CB John Reid, WR Isaiah Coulter
» Series history: Colts lead, 28-9; Colts are 13-6 all-time on the road against the Texans.
» Last matchup in Houston: Nov. 21, 2019; Texans 20, Colts 17.
» Last Colts road victory vs. Texans in Houston: Jan. 5, 2019: Colts 21, Texans 7 (AFC Wild Card Game)
» Of note: This will be the first time the Colts and Texans have ever played in a Week 13 matchup in Houston in their series history. The first and only other time the two teams have played in Week 13 came in the 2002 season, a 19-3 Indy victory at the RCA Dome. In that game, the Colts jumped out to a 19-0 lead until the 3:45 mark of the fourth quarter, when the Texans sneaked onto the scoreboard with a 34-yard Kris Brown field goal. Peyton Manning completed 15-of-28 passes for 190 yards and a touchdown (a 16-yard pass play to tight end Marcus Pollard midway through the first quarter), while the Indy defense sacked Houston quarterback David Carr six times, including three from defensive lineman Brad Scioli.