Colts wide receiver Reggie Wayne sets a career high with 212 receiving yards against the Packers in 2012.

Here's everything you need to know before the Indianapolis Colts take on the Houston Texans in Week 13 of the 2020 NFL season.

NFL Network's Jim Trotter and Michael Silver react to Former NFL quarterback Peyton Manning being selected as a Pro Football Hall of Fame semifinalist for 2021.

NFL Network's Stacey Dales interviews Indianapolis Colts linebacker Darius Leonard after a Week 11 win against the Green Bay Packers.

Here's everything you need to know before the Green Bay Packers take on the Indianapolis Colts in Week 11 of the 2020 NFL season.

Indianapolis Colts quarterback Philip Rivers reacts to passing Dan Marino for 5th-most pass yards in NFL history.

The "Good Morning Football" crew discusses who wins in a head-to-head battle, Tennessee Titans RB Derrick Henry or Indianapolis Colts LB Darius Leonard.

Check out the Indianapolis Colts' greatest plays in their history with the Tennessee Titans.

NFL Network's James Palmer breaks down how the Indianapolis Colts plan to contain Tennessee TItans RB Derrick Henry.

NFL Network's Charley Casserly's keys for Indianapolis Colts vs. Tennessee Titans to win in Week 10.

Here's everything you need to know before the Indianapolis Colts take on the Tennessee Titans in Week 10 of the 2020 NFL season.

NFL Network's Bucky Brooks breaks down why the Indianapolis Colts are a kryptonite matchup for Lamar Jackson and the Baltimore Ravens.

Here's everything you need to know before the Baltimore Ravens take on the Indianapolis Colts in Week 9 of the 2020 NFL season.

Peyton Manning tosses six touchdowns against the Lions on Thanksgiving 2004.

Here's everything you need to know before the Indianapolis Colts take on the Detroit Lions in Week 8 of the 2020 NFL season.

Former Colts defensive end Dwight Freeney relives his spectacular career.

Check out the FedEx Air & Ground nominees from Week 6 of the 2020 NFL season.

Here's everything you need to know before the Cincinnati Bengals take on the Indianapolis Colts in Week 6 of the 2020 NFL season.

Here's everything you need to know before the Indianapolis Colts take on the Cleveland Browns in Week 5 of the 2020 NFL season.

Every player with a PFF grade of 90+ in Week 4

Here's everything you need to know before the Indianapolis Colts take on the Chicago Bears in Week 4 of the 2020 NFL season.

NFL Network's Stacey Dales breaks down the Indianapolis Colts defense ahead of the Colts-Bears Week 4 matchup.

Indianapolis Colts defensive back Xavier Rhodes and tight end Mo Alie-Cox were among players with a PFF grade of 90+ in Week 3 of the NFL season

Indianapolis Colts linebacker Darius Leonard reveals how he got his wedding ring back after it got stuck in the gloves he gave away.

Here's everything you need to know before the New York Jets take on the Indianapolis Colts in Week 3 of the 2020 NFL season.