Ahead of their Week 7 matchup, watch highlights from the Indianapolis Colts win over the San Francisco 49ers in 2005.

Here's everything you need to know before the Indianapolis Colts take on the San Francisco 49ers in Week 7 of the 2021 NFL season.

Watch Indianapolis Colts quarterback Carson Wentz's three most improbable completions from the Week 6 win over the Houston Texans, according to Next Gen Stats.

Here's everything you need to know before the Houston Texans take on the Indianapolis Colts in Week 6 of the 2021 NFL season.

Watch the Indianapolis Colts' top 5 plays from the first five weeks of the 2021 season, according to Next Gen Stats.

Ahead of their Week 5 matchup, watch the Indianapolis Colts' greatest five plays against the Baltimore Ravens.

Peyton Manning tossed four touchdown passes (including No. 300 of career,) Joseph Addai found the end zone three times and the Indianapolis Colts defense forced five turnovers in a 44-20 victory over the Baltimore Ravens under the lights in 2007.

Here's everything you need to know before the Indianapolis Colts take on the Baltimore Ravens in Week 5 of the 2021 NFL season.

Indianapolis Colts DT DeForest Buckner joins "Good Morning Football" to discuss QB Carson Wentz, the Colts' first win of the season and LB Darius Leonard.

Here's everything you need to know before the Indianapolis Colts take on the Miami Dolphins in Week 4 of the 2021 NFL season.

Here's everything you need to know before the Indianapolis Colts take on the Tennessee Titans in Week 3 of the 2021 NFL season.

NFL Network's Steve Wyche shows Indianapolis Colts' "Kicking the Stigma" warm-up T-shirts before Week 2.

Here's everything you need to know before the Los Angeles Rams take on the Indianapolis Colts in Week 2 of the 2021 NFL season.

Indianapolis Colts WR Michael Strachan joins "Good Morning Football" to discuss his journey from the Bahamas to the NFL and to preview the Colts Week 1 matchup vs. the Seattle Seahawks.

Here's everything you need to know before the Seattle Seahawks take on the Indianapolis Colts in Week 1 of the 2021 NFL season.

Indianapolis Colts defensive tackle DeForest Buckner has been voted as the No. 27 player in the NFL on the "Top 100 Players of 2021" rankings.

Indianapolis Colts offensive guard Quenton Nelson has been voted as the No. 33 player in the NFL on the "Top 100 Players of 2021" rankings.

Indianapolis Colts linebacker Darius Leonard has been voted as the No. 37 player in the NFL on the "Top 100 Players of 2021" rankings.

Indianapolis Colts center Ryan Kelly has been voted as the No. 69 player in the NFL on the "Top 100 Players of 2021" rankings.

Indianapolis Colts running back Jonathan Taylor says he's "exceptionally more comfortable" in Colts" offense entering '21.

Pro Football Hall of Fame quarterback Peyton Manning is presented by his dad Archie Manning during the 2021 HOF enshrinement ceremony.

Watch the greatest moments from Peyton Manning's Colts career.

Pro Football Hall of Fame running back Edgerrin James joins "NFL Total Access" to talk about what went into his HOF enshrinement speech and more.

Hall of Fame inductee and former Indianapolis Colts running back Edgerrin James' full speech at the Pro Football HOF Class of 2020 enshrinement ceremony.

Pro Football Hall of Fame Class of 2020 running back Edgerrin James is presented by Indianapolis Colts owner Jim Irsay.