The Indianapolis Colts return home for an AFC South Showdown with the visiting Houston Texans. Get ready for the Week 6 matchup at Lucas Oil Stadium.

The Indianapolis Colts meet with the media ahead of their Week 6 matchup with the Houston Texans.

Indianapolis Colts head coach Frank Reich gives a final injury update ahead of the team's Week 6 matchup with the Houston Texans.

Indianapolis Colts wide receiver T.Y. Hilton speaks with the media ahead of the team's Week 6 matchup with the Houston Texans.

Indianapolis Colts defensive end Kwity Paye speaks with the media ahead of the team's Week 6 matchup with the Houston Texans.

Indianapolis Colts linebacker Darius Leonard speaks with the media ahead of the team's Week 6 matchup with the Houston Texans.

Watch the Indianapolis Colts best plays through the first five weeks of the 2021 season.

Indianapolis Colts defensive back Kenny Moore II was wired for sound for the team's Week 5 matchup with the Baltimore Ravens.

Indianapolis Colts quarterback Carson Wentz speaks with the media ahead of the team's Week 6 matchup with the Houston Texans.

Indianapolis Colts offensive lineman Chris Reed speaks with the media ahead of the team's Week 6 matchup with the Houston Texans.

Indianapolis Colts defensive tackle DeForest Buckner speaks with the media ahead of the team's Week 6 matchup with the Houston Texans.

Indianapolis Colts head coach Frank Reich speaks with the media ahead of the team's Week 6 matchup with the Houston Texans.

Here's everything you need to know before the Houston Texans take on the Indianapolis Colts in Week 6 of the 2021 NFL season.

Watch the Indianapolis Colts' top 5 plays from the first five weeks of the 2021 season, according to Next Gen Stats.

Indianapolis Colts head coach Frank Reich speaks with the media following the team's Week 5 loss to the Baltimore Ravens.

Indianapolis Colts defensive coordinator Matt Eberflus speaks with the media following the team's Week 5 loss to the Baltimore Ravens.

Indianapolis Colts offensive coordinator Marcus Brady speaks with the media following the team's Week 5 loss to the Baltimore Ravens.

Watch the Indianapolis Colts' top plays vs. Baltimore Ravens during Week 5 of the NFL 2021 season.

Indianapolis Colts head coach Frank Reich speaks with the media following the team's matchup with the Baltimore Ravens.

Indianapolis Colts quarterback Carson Wentz speaks with the media following the team's matchup with the Baltimore Ravens.

Indianapolis Colts kicker Rodrigo Blankenship speaks with the media following the team's matchup with the Baltimore Ravens.

Indianapolis Colts running back Jonathan Taylor speaks with the media following the team's matchup with the Baltimore Ravens.

Indianapolis Colts linebacker Darius Leonard speaks with the media following the team's matchup with the Baltimore Ravens.

Indianapolis Colts wide receiver Michael Pittman Jr. speaks with the media following the team's matchup with the Baltimore Ravens.

Watch all of the best plays from Indianapolis Colts quarterback Carson Wentz's 402-yard game in Week 5 of the 2021 season.