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Indianapolis Colts offensive lineman Eric Fisher speaks with the media ahead of the team's matchup with the Los Angeles Rams.

Go behind the scenes at Lucas Oil Stadium as the Indianapolis Colts hosted the Seattle Seahawks in Week 1.

Quarterback Russell Wilson and the Seattle Seahawks' offense had their way against the Indianapolis Colts' defense in the first half of Sunday's 2021 opener at Lucas Oil Stadium. The Indy defense seemed to turn a corner for most of the second half, but it wouldn't be enough in the Colts' 28-16 loss.

Check out a list of stats and notes from the Indianapolis Colts' 2021 season opener against the Seattle Seahawks. 

Indianapolis Colts quarterback Carson Wentz's best plays from Colts Debut vs Seahawks during Week 1 of the 2021 season.

Indianapolis Colts linebacker Darius Leonard speaks with the media following the team's loss to the Seattle Seahawks.

Indianapolis Colts defensive back Kenny Moore II speaks with the media following the team's loss to the Seattle Seahawks.

Indianapolis Colts center Ryan Kelly speaks with the media following the team's loss to the Seattle Seahawks.

Indianapolis Colts quarterback Carson Wentz speaks with the media following the team's loss to the Seattle Seahawks.

Indianapolis Colts head coach Frank Reich speaks with the media following the team's loss to the Seattle Seahawks.

See all the action on the field at Lucas Oil Stadium as the Indianapolis Colts take on the Seattle Seahawks in Week 1 of the 2021 regular season.

Carson Wentz and the Colts kick off the 2021 season on Sunday at 1 p.m. against the Seattle Seahawks at Lucas Oil Stadium. Follow along with updates from writer JJ Stankevitz throughout the game right here. 

Indianapolis Colts quarterback Carson Wentz finds wide receiver Zach Pascal for an 11-yard touchdown against the Seattle Seahawks.

Indianapolis Colts defensive end Kwity Paye recovers running back Chris Carson's fumble against Seattle Seahawks.

Indianapolis Colts defensive tackle DeForest Buckner reintroduces himself to former NFC West rival Seattle Seahawks quarterback Russell Wilson for sack.

Seattle Seahawks quarterback Russell Wilson can't escape Indianapolis Colts safety Khari Willis, Colts on 10-yard sack.

Indianapolis Colts wide receiver Zach Pascal hauls in a bullet from quarterback Carson Wentz to score a 10-yard touchdown vs. Seattle.

Indianapolis Colts wide receiver Parris Campbell hangs on through contact for tough 24-yard grab.

The Indianapolis Colts are on the field at Lucas Oil Stadium as they prepare to face the Seattle Seahawks in Week 1.

The Indianapolis Colts have arrived ahead of their regular season home opener against the Seattle Seahawks.

Indianapolis Colts head coach Frank Reich speaks with Larra Overton about what he wants to see from his team ahead of their Week 1 matchup with the Seattle Seahawks.

Get prepared for the Indianapolis Colts first game of the 2021 regular season as they host the Seattle Seahawks.

The 2021 fantasy football season is finally here and there are plenty of Colts players who could help your team win in Week 1. 

Indianapolis Colts players meet with the media ahead of their week 1 matchup with the Seattle Seahawks.

Indianapolis Colts running back Jonathan Taylor speaks with the media ahead of the team's matchup with the Seattle Seahawks.

Indianapolis Colts head coach Frank Reich gives a final update on his team ahead of their matchup with the Seattle Seahawks.

Indianapolis Colts offensive lineman Julién Davenport speaks with the media ahead of the team's matchup with the Seattle Seahawks.

Indianapolis Colts linebacker Darius Leonard speaks with the media ahead of the team's matchup with the Seattle Seahawks.

Additional inventory for the Week 1 game between Indianapolis and Seattle is now available.

Indianapolis Colts defensive lineman DeForest Buckner speaks with the media ahead of the team's matchup with the Seattle Seahawks.

Indianapolis Colts quarterback Carson Wentz speaks with the media ahead of the team's matchup with the Seattle Seahawks.

Indianapolis Colts head coach Frank Reich speaks with the media ahead of the team's matchup with the Seattle Seahawks.

After an impressive preseason, Paye is listed as one of the Colts' two starting defensive ends in the Week 1 unofficial depth chart. 

Indianapolis Colts offensive coordinator Marcus Brady speaks with the media ahead of the team's week 1 matchup with the Seattle Seahawks.

All the ways Colts fans can watch, live stream and listen to Seattle Seahawks at Indianapolis Colts on Sunday, September 12th 2021 (Week 1).

The first unofficial Colts' depth chart of the 2021 regular season is here. Check it out below. 

The Colts will open the 2021 season at Lucas Oil Stadium against the Seahawks. Here's what you need to know about Seattle's offseason and what to expect in 2021.