Indianapolis Colts Vs. Los Angeles Rams, September 19, 2021

On Sunday Sep. 19th, the Indianapolis Colts will host the Los Angeles Rams at Lucas Oil Stadium in week 2 of the 2021 NFL regular season.

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Indianapolis will host the Los Angeles Rams in Week 2. It will mark the 45th all-time regular season meeting between the teams with the Colts holding a 23-19-2 advantage, including 14-6-2 at home. In the 2017 regular season opener, the Rams hosted and defeated the Colts, 46-9. Running back Marlon Mack registered a rushing touchdown in his NFL debut.

2020 record: 10-6

2021 additions: QB Matthew Stafford, WR DeSean Jackson, P Corey Bojorquez, CB Kareem Orr

2021 losses: QB Jared Goff, S John Johnson, OLB Samson Ebukam, CB Troy Hill, DE Morgan Fox, TE Gerald Everrett, WR Josh Reynolds, RB Malcolm Brown, LS Jake McQuaide, OLB Derek Rivers, OG Austin Blythe, QB Blake Bortles

2021 draft class: WR Tutu Atwell, LB Ernest Jones, DL Bobby Brown III, CB Robert Rochell, WR Jacob Harris, DL Earnest Brown IV, RB Jake Funk, WR Ben Skowronek, LB Chris Garrett

All-time series: 23-19-2

Last matchup: Week 1, 2017 at Los Angeles Memorial Coliseum - Rams 46, Colts 9

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