Indianapolis Colts At Arizona Cardinals, December 25, 2021

On Saturday Dec. 25, the Indianapolis Colts will face the Arizona Cardinals at State Farm Stadium in week 16 of the 2021 NFL regular season.

WEEK 16 • SAT 12/25 • FINAL

Indianapolis Colts 9-6

Arizona Cardinals 10-5

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In Week 16, the Colts will travel to Arizona to face the Cardinals in primetime on Christmas Day. It will mark Indianapolis' first game played on Christmas Day in franchise history and the 17th overall regular season game between the teams with the record tied at 8-8. In Week 2 of the 2017 season, the Cardinals traveled to Indianapolis and defeated the Colts in overtime, 16-13. Tight end Jack Doyle led the team with eight receptions for 79 yards.

Players & Coaches To Know

Indianapolis Colts

Arizona Cardinals

2020 record: 8-8

2021 additions: DE J.J. Watt, K Matt Prater, WR A.J. Green, CB Malcolm Butler, RB James Conner, QB Colt McCoy, S Shawn Williams, OG Brian Winters, TE Ross Travis, WR Antoine Wesley, C Rodney Hudson

2021 losses: RB Kenyan Drake, CB Patrick Peterson, OLB Haason Reddick, TE Dan Arnold, DE Angelo Blackson, C Mason Cole

2021 draft class: LB Zaven Collins, WR Rondale Moore, CB Marco Wilson, EDGE Victor Dimukeje, CB Tay Gowan, S James Wiggins, OL Michal Menet

All-Time series: 8-8

Last matchup: Week 2, 2017 at Lucas Oil Stadium - Cardinals 16, Colts 13 (OT)

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