The Indianapolis Colts Coach of the Week program, presented by Anthem Blue Cross and Blue Shield, awards outstanding high school coaches for their hard work and dedication, as well as their success on the field and in the community.

The Indianapolis Colts and Anthem Blue Cross and Blue Shield will launch the 2012 Coach of the Week program in August. All head coaches in the state of Indiana are eligible regardless of their school size, league or division. Coaches are evaluated on various factors including the coach's impact on his team, school and community, as well as performance of the team. The honorees are selected by a panel of high school football media, former athletic directors and other football representatives from all regions of the State.
In addition, all of the 2012 winners will be recognized at a Colts practice visit, and an on-field ceremony at an Indianapolis Colts home game. Each winning coach will also be presented with a certificate, as well as a $2,000 check for their school's football program. Each award is made possible through a $1,000 contribution from both NFL Charities and Anthem Blue Cross and Blue Shield.
| NAME | SCHOOL | |
| Week 1 | Tony Tinkel | Boone Grove |
| Week 2 | Scott Mannering | Lewis Cass |
| Week 3 | Craig Redman | South Bend Adams |
| Week 4 | Andy Dorrel | Culver Academies |
| Week 5 | Marty Wells | Elwood |
| Week 6 | Chris Barrett | Terre Haute North |
| Week 7 | Jason Hawkins | Charlestown |
| Week 8 | Doug Hurt | Castle |
| Week 9 | Darrin Fisher | Whiteland |
| Week 10 | Derek Moyers | Pike |
| Week 11 | Doug Dinan | Carroll (Fort Wayne) |
| Week 12 | Ty Hunt | Cardinal Ritter |